Manno, Catherine S <br/><br/>
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.  [electronic resource] 

 -  Nature medicine  Mar 2006 
 - 342-7 p.  digital 
<br/><br/> Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1078-8956 
<br/><br/><label>Standard No.: </label>10.1038/nm1358  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Amino Acid Sequence<br/>Animals<br/>Dependovirus--genetics<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Exons--genetics<br/>Factor IX--genetics<br/>Genetic Therapy<br/>Genetic Vectors--administration & dosage<br/>Hemophilia A--genetics<br/>Humans<br/>Interferon-gamma--metabolism<br/>Introns--genetics<br/>Liver--immunology<br/>Male<br/>Mice<br/>Middle Aged<br/>Molecular Sequence Data<br/>Monocytes--metabolism<br/>Transduction, Genetic