TY  - GEN
AU  - Brummelkamp,Thijn R
AU  - Fabius,Armida W M
AU  - Mullenders,Jasper
AU  - Madiredjo,Mandy
AU  - Velds,Arno
AU  - Kerkhoven,Ron M
AU  - Bernards,René
AU  - Beijersbergen,Roderick L
TI  - An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
SN  - 1552-4450
PY  - 2006///0510
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Blotting, Western
KW  - Cell Line, Tumor
KW  - Cells, Cultured
KW  - DNA Damage
KW  - Electronic Data Processing
KW  - Fibroblasts
KW  - metabolism
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, p53
KW  - Genetic Techniques
KW  - Humans
KW  - Imidazoles
KW  - chemistry
KW  - Intracellular Signaling Peptides and Proteins
KW  - Mice
KW  - Microscopy, Fluorescence
KW  - Models, Chemical
KW  - Neoplasms
KW  - drug therapy
KW  - Nuclear Proteins
KW  - Nucleic Acid Hybridization
KW  - Oligonucleotide Array Sequence Analysis
KW  - Phosphoproteins
KW  - Piperazines
KW  - Plasmids
KW  - Proto-Oncogene Proteins c-mdm2
KW  - antagonists & inhibitors
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - Signal Transduction
KW  - Tumor Suppressor Protein p53
KW  - Tumor Suppressor p53-Binding Protein 1
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nchembio774
ER  -