TY - GEN AU - Thompson,Lorin A AU - Liauw,Ann Y AU - Ramanjulu,Mercy M AU - Kasireddy-Polam,Padmaja AU - Mercer,Stephen E AU - Maduskuie,Thomas P AU - Glicksman,Marcie AU - Roach,Arthur H AU - Meredith,Jere E AU - Liu,Rui-Qin AU - Combs,Andrew P AU - Higaki,Jeffrey N AU - Cordell,Barbara AU - Seiffert,Dietmar AU - Zaczek,Robert C AU - Robertson,David W AU - Olson,Richard E TI - Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors SN - 0960-894X PY - 2006///0626 KW - Alzheimer Disease KW - drug therapy KW - Amyloid Precursor Protein Secretases KW - Animals KW - Aspartic Acid Endopeptidases KW - Caprolactam KW - analogs & derivatives KW - Cell Line KW - Dogs KW - Drug Design KW - Drug Evaluation, Preclinical KW - Endopeptidases KW - chemistry KW - Enzyme Inhibitors KW - chemical synthesis KW - Humans KW - Molecular Conformation KW - Stereoisomerism KW - Structure-Activity Relationship KW - Succinates N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2006.01.055 ER -