TY - GEN AU - Houghton,A McGarry AU - Quintero,Pablo A AU - Perkins,David L AU - Kobayashi,Dale K AU - Kelley,Diane G AU - Marconcini,Luiz A AU - Mecham,Robert P AU - Senior,Robert M AU - Shapiro,Steven D TI - Elastin fragments drive disease progression in a murine model of emphysema SN - 0021-9738 PY - 2006///0406 KW - Animals KW - Bronchoalveolar Lavage Fluid KW - Chemotaxis, Leukocyte KW - Disease Models, Animal KW - Disease Progression KW - Elastin KW - physiology KW - Emphysema KW - metabolism KW - Macrophages, Alveolar KW - Matrix Metalloproteinase 12 KW - Metalloendopeptidases KW - deficiency KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Monocytes KW - Peptide Fragments KW - Pulmonary Alveoli KW - Smoking N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI25617 ER -