TY  - GEN
AU  - Cherng,Shiou-Chi
AU  - Huang,Wen-Hsin
AU  - Shiau,Chia-Yang
AU  - Lee,An-Rong
AU  - Chou,Tz-Chong
TI  - Mechanisms of antiplatelet activity of PC-09, a newly synthesized pyridazinone derivative
SN  - 0014-2999
PY  - 2006///0602
KW  - 1-Methyl-3-isobutylxanthine
KW  - pharmacology
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - antagonists & inhibitors
KW  - Adenosine Triphosphate
KW  - metabolism
KW  - Alprostadil
KW  - Animals
KW  - Arachidonic Acid
KW  - Blood Platelets
KW  - drug effects
KW  - Calcium
KW  - Collagen
KW  - Cyclic AMP
KW  - Cyclic GMP
KW  - Dose-Response Relationship, Drug
KW  - Imidazoles
KW  - Indomethacin
KW  - Naphthalenes
KW  - chemistry
KW  - Phosphodiesterase Inhibitors
KW  - Platelet Aggregation
KW  - Platelet Aggregation Inhibitors
KW  - Platelet Glycoprotein GPIIb-IIIa Complex
KW  - biosynthesis
KW  - Pyridazines
KW  - Rabbits
KW  - Thrombin
KW  - Thromboxane A2
KW  - Thromboxane-A Synthase
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ejphar.2005.12.022
ER  -