TY  - GEN
AU  - Chen,Kevin X
AU  - Njoroge,F George
AU  - Arasappan,Ashok
AU  - Venkatraman,Srikanth
AU  - Vibulbhan,Bancha
AU  - Yang,Weiying
AU  - Parekh,Tejal N
AU  - Pichardo,John
AU  - Prongay,Andrew
AU  - Cheng,Kuo-Chi
AU  - Butkiewicz,Nancy
AU  - Yao,Nanhua
AU  - Madison,Vincent
AU  - Girijavallabhan,Viyyoor
TI  - Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles
SN  - 0022-2623
PY  - 2006///0329
KW  - Antiviral Agents
KW  - chemical synthesis
KW  - Biological Availability
KW  - Crystallography, X-Ray
KW  - Cyclization
KW  - Hepacivirus
KW  - drug effects
KW  - Humans
KW  - Leukocyte Elastase
KW  - antagonists & inhibitors
KW  - Macrocyclic Compounds
KW  - Models, Molecular
KW  - Oligopeptides
KW  - Proline
KW  - analogs & derivatives
KW  - Serine Endopeptidases
KW  - chemistry
KW  - Serine Proteinase Inhibitors
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Viral Nonstructural Proteins
KW  - Virus Replication
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm050820s
ER  -