Chen, Kevin X <br/><br/>
Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles.  [electronic resource] 

 -  Journal of medicinal chemistry  Feb 2006 
 - 995-1005 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm050820s  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antiviral Agents--chemical synthesis<br/>Biological Availability<br/>Crystallography, X-Ray<br/>Cyclization<br/>Hepacivirus--drug effects<br/>Humans<br/>Leukocyte Elastase--antagonists & inhibitors<br/>Macrocyclic Compounds--chemical synthesis<br/>Models, Molecular<br/>Oligopeptides--chemical synthesis<br/>Proline--analogs & derivatives<br/>Serine Endopeptidases--chemistry<br/>Serine Proteinase Inhibitors--chemical synthesis<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Viral Nonstructural Proteins--antagonists & inhibitors<br/>Virus Replication