Banes-Berceli, Amy K

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. [electronic resource] - American journal of physiology. Renal physiology Jul 2006 - F116-21 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1931-857X

10.1152/ajprenal.00502.2005 doi


Angiotensin II--physiology
Animals
Anticholesteremic Agents--pharmacology
Blood Glucose--physiology
Cells, Cultured
Collagen Type IV--metabolism
Diabetes Mellitus, Experimental--physiopathology
Diabetic Nephropathies--physiopathology
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Activation--drug effects
Janus Kinase 2
Male
Mesangial Cells--chemistry
Phosphorylation--drug effects
Protein-Tyrosine Kinases--metabolism
Proto-Oncogene Proteins--metabolism
Rats
Rats, Sprague-Dawley
STAT1 Transcription Factor--metabolism
STAT3 Transcription Factor--metabolism
Signal Transduction--drug effects
Simvastatin--pharmacology
Terpenes--pharmacology
rho GTP-Binding Proteins--physiology