Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment. [electronic resource]
- American journal of hypertension Feb 2006
- 129-35 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0895-7061
10.1016/j.amjhyper.2005.08.020 doi
Adrenergic beta-Antagonists--therapeutic use Animals Aorta, Thoracic--metabolism Atenolol--therapeutic use Biomarkers--metabolism Blood Pressure--drug effects Blotting, Northern Blotting, Western Carbazoles--therapeutic use Carvedilol Cells, Cultured Connexin 43--biosynthesis Connexins--biosynthesis Disease Models, Animal Endothelial Cells--metabolism Endothelium, Vascular--metabolism Follow-Up Studies Humans Hypertension--blood Immunohistochemistry In Vitro Techniques Microscopy, Confocal NG-Nitroarginine Methyl Ester--toxicity Propanolamines--therapeutic use Rats Rats, Sprague-Dawley Time Factors Treatment Outcome Umbilical Veins--metabolism Gap Junction alpha-4 Protein