TY  - GEN
AU  - Allan,Rudi K
AU  - Mok,Danny
AU  - Ward,Bryan K
AU  - Ratajczak,Thomas
TI  - Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization
SN  - 0021-9258
PY  - 2006///0510
KW  - Alanine
KW  - chemistry
KW  - Amino Acid Sequence
KW  - Aminocoumarins
KW  - Anti-Bacterial Agents
KW  - Binding Sites
KW  - Coumarins
KW  - DNA, Complementary
KW  - metabolism
KW  - Dimerization
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - Enzyme-Linked Immunosorbent Assay
KW  - Glutathione Transferase
KW  - HSP90 Heat-Shock Proteins
KW  - HeLa Cells
KW  - Humans
KW  - Immunophilins
KW  - Molecular Chaperones
KW  - Molecular Conformation
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Novobiocin
KW  - Plasmids
KW  - Point Mutation
KW  - Protein Binding
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
KW  - Steroids
KW  - Substrate Specificity
KW  - Tacrolimus Binding Proteins
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M512406200
ER  -