TY - GEN AU - Zheng,S Lilly AU - Ju,Jeong-ho AU - Chang,Bao-li AU - Ortner,Elizabeth AU - Sun,Jielin AU - Isaacs,Sarah D AU - Sun,Jishang AU - Wiley,Kathy E AU - Liu,Wennuan AU - Zemedkun,Micheas AU - Walsh,Patrick C AU - Ferretti,James AU - Gruschus,James AU - Isaacs,William B AU - Gelmann,Edward P AU - Xu,Jianfeng TI - Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function SN - 0008-5472 PY - 2006///0223 KW - Amino Acid Sequence KW - Chromosome Segregation KW - Chromosomes, Human, Pair 8 KW - genetics KW - DNA, Neoplasm KW - DNA-Binding Proteins KW - Genetic Linkage KW - Genetic Predisposition to Disease KW - Germ-Line Mutation KW - Homeodomain Proteins KW - Humans KW - Male KW - Middle Aged KW - Models, Molecular KW - Molecular Sequence Data KW - Nuclear Magnetic Resonance, Biomolecular KW - Prostatic Neoplasms KW - Protein Structure, Tertiary KW - RNA, Messenger KW - Structure-Activity Relationship KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/0008-5472.CAN-05-1550 ER -