Reiser, Georg <br/><br/>
Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.  [electronic resource] 

 -  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience   
 - 113-22 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0736-5748 
<br/><br/><label>Standard No.: </label>10.1016/j.ijdevneu.2005.11.002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Animals, Newborn<br/>Astrocytes--drug effects<br/>Biomarkers<br/>Blotting, Western--methods<br/>Brain--cytology<br/>Calcium--metabolism<br/>Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone--pharmacology<br/>Cell Death--drug effects<br/>Cell Survival--drug effects<br/>Cells, Cultured<br/>Cytochromes c--metabolism<br/>Dose-Response Relationship, Drug<br/>Drug Interactions<br/>Hippocampus--cytology<br/>Immunohistochemistry--methods<br/>Membrane Potentials--drug effects<br/>Mitochondria--drug effects<br/>Models, Biological<br/>Organometallic Compounds<br/>Oxygen--metabolism<br/>Phytanic Acid--toxicity<br/>Rats<br/>Rats, Wistar<br/>Reactive Oxygen Species--metabolism<br/>Refsum Disease--diagnosis<br/>Rotenone--pharmacology<br/>Synaptosomes--drug effects<br/>Time Factors<br/>Uncoupling Agents--pharmacology