TY - GEN AU - Hollingworth,Gregory J AU - Carlson,Emma J AU - Castro,José L AU - Chicchi,Gary G AU - Clark,Natalie AU - Cooper,Laura C AU - Dirat,Olivier AU - Salvo,Jerry Di AU - Elliott,Jason M AU - Kilburn,Ruth AU - Kurtz,Marc M AU - Rycroft,Wayne AU - Tattersall,F David AU - Tsao,Kwei-Lan AU - Swain,Christopher J TI - Novel lactam NK1 antagonists with anti-emetic activity SN - 0960-894X PY - 2006///0323 KW - Amides KW - chemistry KW - Animals KW - Antiemetics KW - chemical synthesis KW - Gerbillinae KW - Humans KW - Inhibitory Concentration 50 KW - Lactams KW - Methylation KW - Molecular Structure KW - Receptors, Neurokinin-1 KW - metabolism KW - Structure-Activity Relationship KW - Tachykinins KW - antagonists & inhibitors N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2005.11.111 ER -