Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy. [electronic resource]
- The Journal of biological chemistry Mar 2006
- 5811-20 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M507871200 doi
Animals Cells, Cultured Disease Models, Animal Enzyme Activation GTP-Binding Protein alpha Subunits, Gq-G11--genetics Humans Hypertrophy Isoenzymes--metabolism Male Mice Mice, Transgenic Mitogen-Activated Protein Kinases--metabolism Myocytes, Cardiac--cytology Phospholipase C beta RGS Proteins--genetics RNA, Small Interfering--genetics Rats Rats, Sprague-Dawley Second Messenger Systems--physiology Type C Phospholipases--metabolism