TY - GEN AU - Kono,Mari AU - Dreier,Jennifer L AU - Ellis,Jessica M AU - Allende,Maria L AU - Kalkofen,Danielle N AU - Sanders,Kathleen M AU - Bielawski,Jacek AU - Bielawska,Alicja AU - Hannun,Yusuf A AU - Proia,Richard L TI - Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids SN - 0021-9258 PY - 2006///0510 KW - Alleles KW - Amidohydrolases KW - genetics KW - Animals KW - Blotting, Northern KW - Blotting, Western KW - Cell Membrane KW - metabolism KW - Ceramidases KW - Ceramides KW - chemistry KW - Chromatography, Liquid KW - Genetic Vectors KW - Heterozygote KW - Immunohistochemistry KW - Intestinal Mucosa KW - Intestine, Small KW - Lysophospholipids KW - Mass Spectrometry KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Models, Biological KW - Models, Genetic KW - Neutral Ceramidase KW - Phosphorylation KW - Phosphotransferases (Alcohol Group Acceptor) KW - Polymerase Chain Reaction KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Spectrometry, Mass, Electrospray Ionization KW - Sphingolipids KW - Sphingomyelins KW - Sphingosine KW - analogs & derivatives KW - Time Factors KW - Tissue Distribution N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1074/jbc.M508382200 ER -