The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. [electronic resource]
- The Journal of biological chemistry Feb 2006
- 4816-22 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M508300200 doi
Adaptor Proteins, Signal Transducing Animals Blotting, Western Cell Cycle Cell Proliferation Cells, Cultured Cytosol--metabolism DNA Primers--chemistry Epidermal Growth Factor--metabolism Fibroblasts--metabolism G1 Phase HeLa Cells Humans Intracellular Signaling Peptides and Proteins Membrane Proteins Mice Mice, Transgenic PTEN Phosphohydrolase--metabolism Phosphorylation Plasmids--metabolism Protein Serine-Threonine Kinases Proteins--metabolism Proto-Oncogene Proteins c-akt--metabolism RNA, Small Interfering--metabolism Reverse Transcriptase Polymerase Chain Reaction S Phase Static Electricity Thymidine--chemistry