Tzatsos, Alexandros <br/><br/>
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.  [electronic resource] 

 -  Molecular and cellular biology  Jan 2006 
 - 63-76 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0270-7306 
<br/><br/><label>Standard No.: </label>10.1128/MCB.26.1.63-76.2006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing<br/>Animals<br/>Cells, Cultured<br/>Diabetes Mellitus, Type 2--metabolism<br/>Glucose--metabolism<br/>Humans<br/>Insulin--metabolism<br/>Insulin Receptor Substrate Proteins<br/>Leucine--metabolism<br/>Mice<br/>Monomeric GTP-Binding Proteins--metabolism<br/>Mutation<br/>Neuropeptides--metabolism<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphoproteins--analysis<br/>Phosphorylation--drug effects<br/>Protein Kinases--metabolism<br/>Proteins--genetics<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Ras Homolog Enriched in Brain Protein<br/>Rats<br/>Regulatory-Associated Protein of mTOR<br/>Serine--metabolism<br/>Signal Transduction--drug effects<br/>Sirolimus--pharmacology<br/>TOR Serine-Threonine Kinases