TY - GEN AU - Lee,Clare E AU - Goodfellow,Catherine AU - Javid-Majd,Farah AU - Baker,Edward N AU - Shaun Lott,J TI - The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate SN - 0022-2836 PY - 2006///0227 KW - Amino Acid Sequence KW - Anthranilate Phosphoribosyltransferase KW - chemistry KW - Benzamidines KW - Binding Sites KW - Catalysis KW - Cations, Divalent KW - Conserved Sequence KW - Crystallography, X-Ray KW - Lung KW - microbiology KW - Magnesium KW - Models, Molecular KW - Molecular Sequence Data KW - Mycobacterium tuberculosis KW - enzymology KW - Phosphoribosyl Pyrophosphate KW - Protein Structure, Tertiary KW - Sequence Alignment KW - Sequence Homology, Amino Acid KW - Substrate Specificity KW - Tryptophan KW - biosynthesis KW - ortho-Aminobenzoates N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.jmb.2005.11.016 ER -