TY - GEN AU - Rudek,Michelle A AU - Zhao,Ming AU - Smith,Nicola F AU - Robey,Robert W AU - He,Ping AU - Hallur,Gurulingappa AU - Khan,Saeed AU - Hidalgo,Manuel AU - Jimeno,Antonio AU - Colevas,A Dimitrios AU - Messersmith,Wells A AU - Wolff,Antonio C AU - Baker,Sharyn D TI - In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent SN - 1078-0432 PY - 2006///0124 KW - ATP Binding Cassette Transporter, Subfamily G, Member 2 KW - ATP-Binding Cassette Transporters KW - metabolism KW - Administration, Oral KW - Animals KW - Chromatography, High Pressure Liquid KW - Cytochrome P-450 Enzyme System KW - Drug Therapy, Combination KW - HIV Protease Inhibitors KW - pharmacology KW - Humans KW - In Vitro Techniques KW - Mass Spectrometry KW - Methylurea Compounds KW - blood KW - Mice KW - Microsomes, Liver KW - drug effects KW - Neoplasm Proteins KW - Ritonavir KW - Substrate Specificity KW - Tubulin N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-05-1037 ER -