Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients. [electronic resource]
- Clinical pharmacology and therapeutics Nov 2005
- 520-8 p. digital
Publication Type: Clinical Trial; Journal Article
0009-9236
10.1016/j.clpt.2005.07.007 doi
Adult Antifungal Agents--adverse effects Antipsychotic Agents--pharmacokinetics Chromatography, High Pressure Liquid Cytochrome P-450 CYP3A--genetics Cytochrome P-450 CYP3A Inhibitors Dose-Response Relationship, Drug Drug Interactions Enzyme Inhibitors--adverse effects Female Genotype Half-Life Humans Isoxazoles--blood Itraconazole--adverse effects Male Middle Aged Paliperidone Palmitate Psychiatric Status Rating Scales Pyrimidines--blood Risperidone--blood Schizophrenia--blood