Ersmark, Karolina <br/><br/>
Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Apr 2006 
 - 2197-208 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0968-0896 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2005.11.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Aspartic Acid Endopeptidases--antagonists & inhibitors<br/>Binding Sites<br/>Binding, Competitive<br/>Cathepsin D--antagonists & inhibitors<br/>Crystallography, X-Ray<br/>Cyclization<br/>Drug Design<br/>Humans<br/>Macrocyclic Compounds--chemical synthesis<br/>Models, Chemical<br/>Models, Molecular<br/>Molecular Conformation<br/>Plasmodium falciparum--drug effects<br/>Protease Inhibitors--chemical synthesis<br/>Protozoan Proteins<br/>Structure-Activity Relationship