Zhang, Tian-Tai

Pharmacological efficacy of CPU 86017 on hypoxic pulmonary hypertension in rats: mediated by direct inhibition of calcium channels and antioxidant action, but indirect effects on the ET-1 pathway. [electronic resource] - Journal of cardiovascular pharmacology Dec 2005 - 727-34 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0160-2446

10.1097/01.fjc.0000184470.58047.79 doi


Animals
Antioxidants--therapeutic use
Berberine--analogs & derivatives
Calcium Channel Blockers--therapeutic use
Calcium Channels, L-Type--drug effects
Endothelin-1--antagonists & inhibitors
Hypertension, Pulmonary--drug therapy
Hypertrophy, Right Ventricular--drug therapy
Hypoxia--complications
Male
Malondialdehyde--analysis
Nitric Oxide--biosynthesis
Nitric Oxide Synthase--metabolism
Oxidative Stress--drug effects
Pulmonary Artery--pathology
Rats
Rats, Sprague-Dawley