Jones, Philip <br/><br/>
Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Feb 2006 
 - 872-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2005.11.012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>GABA Agonists--chemical synthesis<br/>GABA-A Receptor Agonists<br/>Hydrolysis<br/>Isoxazoles--chemical synthesis<br/>Macaca mulatta<br/>Mice<br/>Molecular Conformation<br/>Protein Subunits--agonists<br/>Rats<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Tissue Distribution<br/>Triazines--chemical synthesis