TY - GEN AU - Vidal,Paloma AU - Timm,David AU - Broughton,Howard AU - Chen,Shu-Hui AU - Martín,José A AU - Rivera-Sagredo,Alfonso AU - McCarthy,James R AU - Shapiro,Michael J AU - Espinosa,Juan F TI - Preorganization of the hydroxyethylene dipeptide isostere: the preferred conformation in solution resembles the conformation bound to BACE SN - 0022-2623 PY - 2006///0209 KW - Amyloid Precursor Protein Secretases KW - Aspartic Acid Endopeptidases KW - Crystallography, X-Ray KW - Dipeptides KW - chemistry KW - Endopeptidases KW - Humans KW - Leucine KW - Magnetic Resonance Spectroscopy KW - Models, Molecular KW - Molecular Conformation KW - Phenylalanine KW - Protease Inhibitors KW - Solutions KW - Valine N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm050631+ ER -