Vidal, Paloma Preorganization of the hydroxyethylene dipeptide isostere: the preferred conformation in solution resembles the conformation bound to BACE. [electronic resource] - Journal of medicinal chemistry Dec 2005 - 7623-7 p. digital Publication Type: Journal Article ISSN: 0022-2623 Standard No.: 10.1021/jm050631+ doi Subjects--Topical Terms: Amyloid Precursor Protein SecretasesAspartic Acid EndopeptidasesCrystallography, X-RayDipeptides--chemistryEndopeptidases--chemistryHumansLeucine--chemistryMagnetic Resonance SpectroscopyModels, MolecularMolecular ConformationPhenylalanine--chemistryProtease Inhibitors--chemistrySolutionsValine--chemistry