Bermúdez-Humarán, Luis G <br/><br/>
A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors.  [electronic resource] 

 -  Journal of immunology (Baltimore, Md. : 1950)  Dec 2005 
 - 7297-302 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-1767 
<br/><br/><label>Standard No.: </label>10.4049/jimmunol.175.11.7297  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Intranasal<br/>Animals<br/>CD4-Positive T-Lymphocytes<br/>CD8-Positive T-Lymphocytes--immunology<br/>Cancer Vaccines--administration & dosage<br/>Cell Line, Tumor<br/>Cell Transplantation<br/>Disease Models, Animal<br/>Female<br/>Human papillomavirus 16--immunology<br/>Immunity, Mucosal--immunology<br/>Interleukin-12--biosynthesis<br/>Lactococcus lactis--genetics<br/>Mice<br/>Nasal Mucosa--immunology<br/>Neoplasm Transplantation<br/>Oncogene Proteins, Viral--biosynthesis<br/>Papillomavirus E7 Proteins<br/>Papillomavirus Infections--prevention & control<br/>Papillomavirus Vaccines<br/>Recombinant Proteins--biosynthesis<br/>Tumor Virus Infections--immunology<br/>Uterine Cervical Neoplasms--immunology<br/>Viral Vaccines--administration & dosage