TY  - GEN
AU  - de Luca,Carl
AU  - Kowalski,Timothy J
AU  - Zhang,Yiying
AU  - Elmquist,Joel K
AU  - Lee,Charlotte
AU  - Kilimann,Manfred W
AU  - Ludwig,Thomas
AU  - Liu,Shun-Mei
AU  - Chua,Streamson C
TI  - Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
SN  - 0021-9738
PY  - 2006///0206
KW  - Agouti-Related Protein
KW  - Alleles
KW  - Animals
KW  - Blood Glucose
KW  - metabolism
KW  - Body Composition
KW  - Body Weight
KW  - Cold Temperature
KW  - DNA, Complementary
KW  - Diabetes Mellitus
KW  - genetics
KW  - Female
KW  - Fertility
KW  - Gene Expression Regulation
KW  - Genetic Therapy
KW  - methods
KW  - Genotype
KW  - Glucose
KW  - Homeostasis
KW  - Homozygote
KW  - Hypothalamus
KW  - pathology
KW  - In Situ Hybridization
KW  - Infertility
KW  - Infertility, Female
KW  - therapy
KW  - Infertility, Male
KW  - Insulin
KW  - Intercellular Signaling Peptides and Proteins
KW  - Male
KW  - Mice
KW  - Mice, Transgenic
KW  - Neurons
KW  - Neuropeptide Y
KW  - Obesity
KW  - Peptides
KW  - chemistry
KW  - Phenotype
KW  - Phosphopyruvate Hydratase
KW  - Polymerase Chain Reaction
KW  - Pro-Opiomelanocortin
KW  - Promoter Regions, Genetic
KW  - Protein Isoforms
KW  - Proteins
KW  - Rats
KW  - Receptors, Cell Surface
KW  - Receptors, Leptin
KW  - Signal Transduction
KW  - Synapsins
KW  - Time Factors
KW  - Tissue Distribution
KW  - Transgenes
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1172/JCI24059
ER  -