TY  - GEN
AU  - Cookson,Jennifer C
AU  - Heald,Robert A
AU  - Stevens,Malcolm F G
TI  - Antitumor polycyclic acridines. 17. Synthesis and pharmaceutical profiles of pentacyclic acridinium salts designed to destabilize telomeric integrity
SN  - 0022-2623
PY  - 2006///0117
KW  - Acridines
KW  - chemical synthesis
KW  - Animals
KW  - Antineoplastic Agents
KW  - Cell Line, Tumor
KW  - Cytochrome P-450 Enzyme System
KW  - metabolism
KW  - Drug Screening Assays, Antitumor
KW  - Drug Stability
KW  - Flow Cytometry
KW  - Heterocyclic Compounds, 4 or More Rings
KW  - Humans
KW  - In Vitro Techniques
KW  - Microscopy, Confocal
KW  - Microsomes, Liver
KW  - drug effects
KW  - Rats
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Telomerase
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm058031y
ER  -