TY  - GEN
AU  - Henry,L Keith
AU  - Field,Julie R
AU  - Adkins,Erika M
AU  - Parnas,M Laura
AU  - Vaughan,Roxanne A
AU  - Zou,Mu-Fa
AU  - Newman,Amy H
AU  - Blakely,Randy D
TI  - Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants
SN  - 0021-9258
PY  - 2006///0307
KW  - Adrenergic Uptake Inhibitors
KW  - pharmacology
KW  - Amino Acid Sequence
KW  - Animals
KW  - Antidepressive Agents
KW  - Binding Sites
KW  - Binding, Competitive
KW  - Blotting, Western
KW  - Cadmium
KW  - chemistry
KW  - Cell Line
KW  - Cell Membrane
KW  - metabolism
KW  - Citalopram
KW  - Clomipramine
KW  - Cocaine
KW  - analogs & derivatives
KW  - Cysteine
KW  - Dopamine Uptake Inhibitors
KW  - Fluoxetine
KW  - HeLa Cells
KW  - Humans
KW  - Immunoprecipitation
KW  - Isoleucine
KW  - Kinetics
KW  - LLC-PK1 Cells
KW  - Mazindol
KW  - Methionine
KW  - Mice
KW  - Models, Chemical
KW  - Molecular Sequence Data
KW  - Mutation
KW  - N-Methyl-3,4-methylenedioxyamphetamine
KW  - Nomifensine
KW  - Protein Binding
KW  - Protein Structure, Tertiary
KW  - Protein Transport
KW  - Radiopharmaceuticals
KW  - Receptors, Serotonin
KW  - Serotonin
KW  - Selective Serotonin Reuptake Inhibitors
KW  - Species Specificity
KW  - Stereoisomerism
KW  - Substrate Specificity
KW  - Tyrosine
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M505055200
ER  -