TY - GEN AU - Sorsa,T AU - Golub,L M TI - Is the excessive inhibition of matrix metalloproteinases (MMPs) by potent synthetic MMP inhibitors (MMPIs) desirable in periodontitis and other inflammatory diseases? That is: 'Leaky' MMPIs vs excessively efficient drugs SN - 1354-523X PY - 2006///0110 KW - Animals KW - Doxycycline KW - analogs & derivatives KW - Humans KW - Matrix Metalloproteinase Inhibitors KW - Matrix Metalloproteinases KW - physiology KW - Periodontitis KW - drug therapy KW - Phenylalanine KW - Protease Inhibitors KW - therapeutic use KW - Rats KW - Thiophenes N1 - Publication Type: Comment; Letter UR - https://doi.org/10.1111/j.1601-0825.2005.01160.x ER -