TY - GEN AU - Seong,Hyun-A AU - Jung,Haiyoung AU - Choi,Hueng-Sik AU - Kim,Kyong-Tai AU - Ha,Hyunjung TI - Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein SN - 0021-9258 PY - 2006///0227 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - Active Transport, Cell Nucleus KW - Androstadienes KW - pharmacology KW - Apoptosis KW - Catalytic Domain KW - Cell Death KW - Cell Line KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Enzyme Inhibitors KW - Gene Expression Regulation, Enzymologic KW - Genes, Reporter KW - Humans KW - Insulin KW - metabolism KW - Luciferases KW - Microscopy, Confocal KW - Microscopy, Fluorescence KW - Neoplasm Proteins KW - chemistry KW - Phosphoinositide-3 Kinase Inhibitors KW - Plasmids KW - Protein Binding KW - Protein Serine-Threonine Kinases KW - Protein Structure, Tertiary KW - RNA, Small Interfering KW - RNA-Binding Proteins KW - Signal Transduction KW - Smad3 Protein KW - Smad7 Protein KW - Time Factors KW - Transcription, Genetic KW - Transfection KW - Transforming Growth Factor beta KW - Tumor Necrosis Factor-alpha KW - Two-Hybrid System Techniques KW - Up-Regulation KW - Wortmannin N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M507539200 ER -