Linton, Steven D <br/><br/>
First-in-class pan caspase inhibitor developed for the treatment of liver disease.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 2005 
 - 6779-82 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm050307e  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Alanine Transaminase--blood<br/>Animals<br/>Apoptosis--drug effects<br/>Aspartate Aminotransferases--blood<br/>Biological Availability<br/>Caspase 3<br/>Caspase Inhibitors<br/>Cholestasis--drug therapy<br/>Clinical Trials, Phase I as Topic<br/>Half-Life<br/>Hepatitis C, Chronic--drug therapy<br/>Hepatocytes--drug effects<br/>Humans<br/>Jurkat Cells<br/>Liver--drug effects<br/>Liver Diseases--drug therapy<br/>Mice<br/>Pentanoic Acids--chemical synthesis<br/>Rats<br/>Structure-Activity Relationship