TY  - GEN
AU  - Rojo,Isabel
AU  - Martín,José Alfredo
AU  - Broughton,Howard
AU  - Timm,David
AU  - Erickson,Jon
AU  - Yang,Hsiu-Chiung
AU  - McCarthy,James R
TI  - Macrocyclic peptidomimetic inhibitors of beta-secretase (BACE): first X-ray structure of a macrocyclic peptidomimetic-BACE complex
SN  - 0960-894X
PY  - 2006///0321
KW  - Alzheimer Disease
KW  - drug therapy
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Protein Precursor
KW  - chemistry
KW  - Animals
KW  - Aspartic Acid Endopeptidases
KW  - Cell Line
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Endopeptidases
KW  - Humans
KW  - Kinetics
KW  - Models, Chemical
KW  - Models, Molecular
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2005.09.003
ER  -