Rojo, Isabel <br/><br/>
Macrocyclic peptidomimetic inhibitors of beta-secretase (BACE): first X-ray structure of a macrocyclic peptidomimetic-BACE complex.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jan 2006 
 - 191-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0960-894X 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2005.09.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--drug therapy<br/>Amyloid Precursor Protein Secretases<br/>Amyloid beta-Protein Precursor--chemistry<br/>Animals<br/>Aspartic Acid Endopeptidases<br/>Cell Line<br/>Chemistry, Pharmaceutical--methods<br/>Crystallography, X-Ray--methods<br/>Drug Design<br/>Endopeptidases--chemistry<br/>Humans<br/>Kinetics<br/>Models, Chemical<br/>Models, Molecular<br/>Protein Conformation<br/>Protein Structure, Tertiary