Soloshonok, Vadim A

Michael addition reactions between chiral equivalents of a nucleophilic glycine and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general method for efficient preparation of beta-substituted pyroglutamic acids. Case of topographically controlled stereoselectivity. [electronic resource] - Journal of the American Chemical Society Nov 2005 - 15296-303 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0002-7863

10.1021/ja0535561 doi


Catalysis
Glycine--chemistry
Kinetics
Models, Chemical
Molecular Structure
Nickel--chemistry
Oxazolidinones--chemistry
Pyrrolidonecarboxylic Acid--chemistry
Schiff Bases--chemistry
Spectrometry, Mass, Fast Atom Bombardment
Stereoisomerism