Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Nov 2005
- 5732-43 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural
0022-1767
10.4049/jimmunol.175.9.5732 doi
Animals Bone Marrow Transplantation--immunology Graft vs Host Disease--prevention & control Graft vs Tumor Effect--drug effects Immunosuppressive Agents--pharmacology Interleukin-4--physiology Mice Mice, Inbred BALB C Mice, Inbred C57BL Sirolimus--pharmacology Th2 Cells--drug effects Tissue Donors