TY - GEN AU - Bergman,Andries M AU - Eijk,Paul P AU - Ruiz van Haperen,Veronique W T AU - Smid,Kees AU - Veerman,Gijsbert AU - Hubeek,Isabelle AU - van den Ijssel,Paul AU - Ylstra,Bauke AU - Peters,Godefridus J TI - In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant SN - 0008-5472 PY - 2005///1219 KW - Animals KW - Blotting, Western KW - Colonic Neoplasms KW - drug therapy KW - Cytidine Deaminase KW - Deoxycytidine KW - analogs & derivatives KW - Deoxycytidine Kinase KW - biosynthesis KW - Deoxycytosine Nucleotides KW - metabolism KW - Drug Resistance, Neoplasm KW - Female KW - Gene Expression Profiling KW - Mice KW - Mice, Inbred BALB C KW - Nucleoside Deaminases KW - Oligonucleotide Array Sequence Analysis KW - Protein Subunits KW - Ribonucleotide Reductases KW - Gemcitabine N1 - Publication Type: Journal Article UR - https://doi.org/10.1158/0008-5472.CAN-05-0989 ER -