TY - GEN AU - Mezhir,James J AU - Advani,Sunil J AU - Smith,Kerrington D AU - Darga,Thomas E AU - Poon,Alice P W AU - Schmidt,Hank AU - Posner,Mitchell C AU - Roizman,Bernard AU - Weichselbaum,Ralph R TI - Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses SN - 0008-5472 PY - 2005///1219 KW - Animals KW - Chlorocebus aethiops KW - DNA, Viral KW - biosynthesis KW - Enzyme Activation KW - Gene Expression Regulation, Viral KW - radiation effects KW - HeLa Cells KW - Herpesvirus 1, Human KW - enzymology KW - Humans KW - MAP Kinase Signaling System KW - Mice KW - Neoplasms KW - therapy KW - Pancreatic Neoplasms KW - Phosphorylation KW - Promoter Regions, Genetic KW - Rabbits KW - Up-Regulation KW - Vero Cells KW - Xenograft Model Antitumor Assays KW - p38 Mitogen-Activated Protein Kinases KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-05-1927 ER -