Ren, Shu-yue

Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase. [electronic resource] - Experimental hematology Oct 2005 - 1222-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0301-472X

10.1016/j.exphem.2005.06.030 doi


Amino Acid Substitution
Animals
Cell Line, Tumor
Fusion Proteins, bcr-abl
Hematopoietic Stem Cells--metabolism
Humans
Immunoprecipitation--methods
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--genetics
Mice
Mutagenesis, Site-Directed
Philadelphia Chromosome
Phosphatidylinositol 3-Kinases--genetics
Point Mutation--genetics
Protein Binding
Protein Subunits--genetics
Protein-Tyrosine Kinases--genetics
Proto-Oncogene Proteins--genetics
Signal Transduction
src Homology Domains--genetics