Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. [electronic resource]
- The Journal of pharmacology and experimental therapeutics Jan 2006
- 466-75 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
10.1124/jpet.105.091686 doi
Animals Carrageenan Chemical Phenomena Chemistry, Physical Cyclooxygenase Inhibitors--pharmacology Dinoprostone--metabolism Dose-Response Relationship, Drug Enzyme Inhibitors--administration & dosage Hot Temperature Hyperalgesia--chemically induced Injections, Intraperitoneal Injections, Spinal Male Microdialysis Oxidation-Reduction Phospholipases A--antagonists & inhibitors Phospholipases A2 Rats Rats, Sprague-Dawley Receptor, Cannabinoid, CB1--antagonists & inhibitors Spinal Cord--drug effects Substance P gamma-Aminobutyric Acid--administration & dosage