TY  - GEN
AU  - Netea,M G
AU  - Ferwerda,G
AU  - de Jong,D J
AU  - Girardin,S E
AU  - Kullberg,B J
AU  - van der Meer,J W M
TI  - NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype
SN  - 0300-2977
PY  - 2005///1230
KW  - Acetylmuramyl-Alanyl-Isoglutamine
KW  - administration & dosage
KW  - Alleles
KW  - Case-Control Studies
KW  - Crohn Disease
KW  - genetics
KW  - Gene Expression Regulation
KW  - Genetic Predisposition to Disease
KW  - Homozygote
KW  - Humans
KW  - Interleukin-1
KW  - biosynthesis
KW  - Intracellular Signaling Peptides and Proteins
KW  - Leukocytes, Mononuclear
KW  - immunology
KW  - Lipopeptides
KW  - Mutation
KW  - Nod2 Signaling Adaptor Protein
KW  - Oligopeptides
KW  - Peptidoglycan
KW  - Polymerase Chain Reaction
KW  - Signal Transduction
KW  - Toll-Like Receptor 2
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ER  -