Malawska, Barbara

Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity. [electronic resource] - Farmaco (Societa chimica italiana : 1989) Oct 2005 - 793-803 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-827X

10.1016/j.farmac.2005.08.002 doi


Adrenergic alpha-Agonists--chemical synthesis
Animals
Anti-Arrhythmia Agents--chemical synthesis
Antihypertensive Agents--chemical synthesis
Arrhythmias, Cardiac--drug therapy
Blood Pressure--drug effects
Hypertension--drug therapy
Male
Mice
Molecular Structure
Pyrrolidines--chemical synthesis
Radioligand Assay
Rats
Rats, Wistar
Receptors, Adrenergic, alpha--metabolism
Toxicity Tests, Acute