TY - GEN AU - Tomita,K AU - Tamiya,G AU - Ando,S AU - Ohsumi,K AU - Chiyo,T AU - Mizutani,A AU - Kitamura,N AU - Toda,K AU - Kaneko,T AU - Horie,Y AU - Han,J-Y AU - Kato,S AU - Shimoda,M AU - Oike,Y AU - Tomizawa,M AU - Makino,S AU - Ohkura,T AU - Saito,H AU - Kumagai,N AU - Nagata,H AU - Ishii,H AU - Hibi,T TI - Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice SN - 0017-5749 PY - 2006///0314 KW - Animals KW - Apoptosis KW - Cell Adhesion Molecules KW - biosynthesis KW - Choline Deficiency KW - complications KW - Fatty Liver KW - Gene Expression Regulation KW - Kupffer Cells KW - metabolism KW - Liver Cirrhosis, Experimental KW - etiology KW - Male KW - Methionine KW - deficiency KW - Mice KW - Mice, Knockout KW - Mitochondria, Liver KW - physiology KW - Mutation KW - RNA, Messenger KW - genetics KW - Receptors, Tumor Necrosis Factor, Type I KW - Receptors, Tumor Necrosis Factor, Type II KW - Reverse Transcriptase Polymerase Chain Reaction KW - methods KW - Signal Transduction KW - Tissue Inhibitor of Metalloproteinase-1 KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article UR - https://doi.org/10.1136/gut.2005.071118 ER -