TY - GEN AU - Ota,H AU - Tokunaga,E AU - Chang,K AU - Hikasa,M AU - Iijima,K AU - Eto,M AU - Kozaki,K AU - Akishita,M AU - Ouchi,Y AU - Kaneki,M TI - Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells SN - 0950-9232 PY - 2006///0216 KW - Benzamides KW - pharmacology KW - Breast Neoplasms KW - drug therapy KW - Cellular Senescence KW - drug effects KW - Enzyme Activation KW - Epidermal Growth Factor KW - ErbB Receptors KW - metabolism KW - Genes, ras KW - physiology KW - Histone Deacetylase Inhibitors KW - Humans KW - Insulin-Like Growth Factor I KW - Lung Neoplasms KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Naphthols KW - Phosphatidylinositol 3-Kinases KW - Phosphorylation KW - Plasminogen Activator Inhibitor 1 KW - Proto-Oncogene Proteins c-akt KW - Receptor, IGF Type 1 KW - Signal Transduction KW - Sirtuin 1 KW - Sirtuins KW - antagonists & inhibitors KW - Tumor Cells, Cultured KW - Tyrosine KW - beta-Galactosidase KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1038/sj.onc.1209049 ER -