TY - GEN AU - Wang,Jian-Guo AU - Mahmud,Shawn A AU - Thompson,Jacob A AU - Geng,Jian-Guo AU - Key,Nigel S AU - Slungaard,Arne TI - The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states SN - 0006-4971 PY - 2006///0207 KW - Early Growth Response Protein 1 KW - metabolism KW - Electrophoretic Mobility Shift Assay KW - Endothelium, Vascular KW - cytology KW - Eosinophil Peroxidase KW - Eosinophils KW - enzymology KW - Humans KW - Lipopolysaccharides KW - pharmacology KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - NF-kappa B KW - Oxidants KW - Oxidation-Reduction KW - Phagocytes KW - Phosphatidylinositol 3-Kinases KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Thiocyanates KW - Thromboplastin KW - Thrombosis KW - immunology KW - Transcription Factor AP-1 KW - Transcription Factor RelA KW - genetics KW - Transcription, Genetic KW - Umbilical Veins KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1182/blood-2005-05-2152 ER -