TY - GEN AU - Yee,Karen W L AU - Hagey,Anne AU - Verstovsek,Srdan AU - Cortes,Jorge AU - Garcia-Manero,Guillermo AU - O'Brien,Susan M AU - Faderl,Stefan AU - Thomas,Deborah AU - Wierda,William AU - Kornblau,Steven AU - Ferrajoli,Alessandra AU - Albitar,Maher AU - McKeegan,Evelyn AU - Grimm,David R AU - Mueller,Toby AU - Holley-Shanks,Rhonda R AU - Sahelijo,Leonardo AU - Gordon,Gary B AU - Kantarjian,Hagop M AU - Giles,Francis J TI - Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies SN - 1078-0432 PY - 2005///1108 KW - AC133 Antigen KW - Acute Disease KW - Adult KW - Aged KW - Antigens, CD KW - analysis KW - Antineoplastic Agents KW - adverse effects KW - CD146 Antigen KW - Constipation KW - chemically induced KW - Diarrhea KW - Dose-Response Relationship, Drug KW - Drug Resistance, Neoplasm KW - Endothelial Cells KW - chemistry KW - Female KW - Glycoproteins KW - Hematologic Neoplasms KW - blood KW - Humans KW - Leukemia KW - Leukocyte Common Antigens KW - Male KW - Microtubules KW - metabolism KW - Middle Aged KW - Mutation KW - Myelodysplastic Syndromes KW - Nausea KW - Neoplasm Recurrence, Local KW - Neoplastic Cells, Circulating KW - Neural Cell Adhesion Molecules KW - Peptides KW - Platelet Endothelial Cell Adhesion Molecule-1 KW - Sulfonamides KW - Treatment Outcome KW - Tubulin KW - genetics KW - Vomiting N1 - Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-05-0650 ER -