Yee, Karen W L

Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Sep 2005 - 6615-24 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

1078-0432

10.1158/1078-0432.CCR-05-0650 doi


AC133 Antigen
Acute Disease
Adult
Aged
Antigens, CD--analysis
Antineoplastic Agents--adverse effects
CD146 Antigen
Constipation--chemically induced
Diarrhea--chemically induced
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
Endothelial Cells--chemistry
Female
Glycoproteins--analysis
Hematologic Neoplasms--blood
Humans
Leukemia--blood
Leukocyte Common Antigens--analysis
Male
Microtubules--metabolism
Middle Aged
Mutation
Myelodysplastic Syndromes--blood
Nausea--chemically induced
Neoplasm Recurrence, Local
Neoplastic Cells, Circulating--chemistry
Neural Cell Adhesion Molecules--analysis
Peptides--analysis
Platelet Endothelial Cell Adhesion Molecule-1--analysis
Sulfonamides--adverse effects
Treatment Outcome
Tubulin--genetics
Vomiting--chemically induced