Bolbrinker, Juliane

Expression and response to angiotensin-converting enzyme inhibition of matrix metalloproteinases 2 and 9 in renal glomerular damage in young transgenic rats with renin-dependent hypertension. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jan 2006 - 8-16 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3565

10.1124/jpet.105.093112 doi


Angiotensin-Converting Enzyme Inhibitors--pharmacology
Animals
Animals, Genetically Modified
Blood Pressure--drug effects
Blotting, Western
Body Weight--drug effects
Gelatin--metabolism
Gene Expression Regulation, Enzymologic--drug effects
Glomerular Mesangium--physiopathology
Hypertension--physiopathology
Immunohistochemistry
Kidney Diseases--physiopathology
Male
Matrix Metalloproteinase 2--biosynthesis
Matrix Metalloproteinase 9--biosynthesis
Matrix Metalloproteinase Inhibitors
RNA, Messenger--biosynthesis
Rats
Rats, Sprague-Dawley
Renin-Angiotensin System--physiology
Reverse Transcriptase Polymerase Chain Reaction
Serine Endopeptidases--genetics
Tissue Inhibitor of Metalloproteinase-1--physiology
Tissue Inhibitor of Metalloproteinase-2--physiology
Transforming Growth Factor beta--biosynthesis
Transforming Growth Factor beta1