TY - GEN AU - Blanco-Aparicio,Carmen AU - Pequeño,Belen AU - Moneo,Victoria AU - Romero,Lourdes AU - Leal,Juan F M AU - Velasco,Juan AU - Fominaya,Jesús AU - Carnero,Amancio TI - Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria SN - 0959-4973 PY - 2005///1216 KW - Carcinoma KW - genetics KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cell Survival KW - Chromones KW - pharmacology KW - DNA-Binding Proteins KW - Deoxycytidine KW - analogs & derivatives KW - Enzyme Inhibitors KW - Female KW - Gene Expression KW - Genes, Tumor Suppressor KW - Humans KW - Inhibitory Concentration 50 KW - Leiomyosarcoma KW - Melanoma KW - Mitochondria KW - Morpholines KW - Neoplasms KW - Nuclear Proteins KW - PTEN Phosphohydrolase KW - metabolism KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Protein Transport KW - Proto-Oncogene Proteins c-akt KW - Reverse Transcriptase Polymerase Chain Reaction KW - Tumor Protein p73 KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor Proteins KW - bcl-2-Associated X Protein KW - bcl-X Protein KW - Gemcitabine N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1097/01.cad.0000180117.93535.cf ER -