TY - GEN AU - Niida,Hiroyuki AU - Tsuge,Shinji AU - Katsuno,Yuko AU - Konishi,Akimitsu AU - Takeda,Naoki AU - Nakanishi,Makoto TI - Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe SN - 0021-9258 PY - 2006///0203 KW - Animals KW - Apoptosis KW - Ataxia Telangiectasia Mutated Proteins KW - Base Sequence KW - CDC2 Protein Kinase KW - genetics KW - Cell Cycle Proteins KW - metabolism KW - Cell Line KW - Checkpoint Kinase 1 KW - Cyclin B KW - Cytochromes c KW - DNA Damage KW - DNA-Binding Proteins KW - Enzyme Activation KW - Humans KW - Mice KW - Mitosis KW - physiology KW - Protein Kinases KW - deficiency KW - Protein Serine-Threonine Kinases KW - RNA, Small Interfering KW - Transfection KW - Tumor Suppressor Protein p53 KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M505009200 ER -